منابع مشابه
[Granulosa cell tumors of the ovary].
Ovarian granulosa cell tumors (TGO) are rare neoplasms. They arise from sex cord stromal cells of the ovaries. They are characterized by their slow natural history, and their tendency to relapse long time after the initial diagnosis. Complete staging surgery of the disease is the cornerstone of treatment. Chemotherapy is indicated for localized tumors with a high risk of recurrence, and for rec...
متن کاملGranulosa Cell – Stromal Tumors: An Immunohistochemical Study Including Comparison of Calretinin and Inhibin
Background and Objective: Histopathological evaluation of granulosa cell tumors (GCT) of the ovary may be confused morphologically with a wide variety of the tumors. Immunohistochemical staining for inhibin and calretinin can be used for better diagnosis. Although it has been suggested that inhibin can be a sensitive marker for GCT, it maybe had negative results in some cases. In addition, cal...
متن کاملNatural history of granulosa cell tumors of the ovary
Kalfa et al.: Genome Medicine 2009, 1:81 Abstract Granulosa cell tumors (GCTs) of the ovary belong to the group of ovarian sex-cord stromal tumors and represent 5 to 10% of ovarian malignancies. GCTs exhibit several morphological, biochemical and hormonal features of normal proliferating preovulatory granulosa cells, such as estrogen biosynthesis. Prognostic factors of this condition are lackin...
متن کاملThe vascular system of two transplantable mouse granulosa-cell tumors.
Successful transplants of neoplastic tissue acquire a blood supply from the host vascular system; the process of this acquisition and the nature of the acquired vascular system are at best poorly understood. Coman and Sheldon (2) observed that the first visible effect of a transplanted tumor was an intense hyperemia in the region around the transplant; however, Molomut e ta / . (5) reported tha...
متن کاملImmunohistochemical diagnosis of canine ovarian epithelial and granulosa cell tumors.
In humans and canines, the morphology of granulosa cell tumors is extremely variable and causes diagnostic difficulties. In human pathology, immunohistochemistry has been widely used for the diagnosis of granulosa cell tumors, whereas, limited studies are present in canine species. The aim of this study was to investigate the expression of cytokeratins, vimentin, and inhibin-alpha in canine nor...
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ژورنال
عنوان ژورنال: International Journal of Gynecological Pathology
سال: 2017
ISSN: 0277-1691
DOI: 10.1097/pgp.0000000000000325